RSMUS.comSalesforce Dreamforce 2025 marked a pivotal moment for the nonprofit sector. With the unveiling of Agentforce 360 and Agentforce Nonprofit, Salesforce redefined how mission-driven organizations can harness AI to scale impact, streamline operations, and deepen engagement. This shift represents a move toward more intelligent, proactive, and human-centered technology.
Agentforce Nonprofit: A New Era
Just one year ago at Dreamforce 2024, Salesforce introduced Agentforce as a bold vision for AI-powered nonprofit transformation. At Dreamforce 2025, that vision became reality. Nonprofit Cloud has evolved into Agentforce Nonprofit, a complete reinvention and now part of the broader Agentforce 360 platform. Built on the principles of the Agentic Enterprise, Agentforce Nonprofit empowers organizations to transition from manual workflows to AI-driven engagement. Organizations can now operate with greater agility, precision, and empathy.
Addressing Sector-Wide Challenges
Nonprofits today face increasing demand for services, limited funding, and staff burnout. Agentforce Nonprofit helps tackle these challenges by introducing AI agents that automate routine tasks, personalize donor outreach, and streamline program delivery. This allows teams to focus more on their mission and less on administrative burdens.
AI Adoption Is Accelerating
AI adoption among nonprofits has surged significantly in the past year. According to Salesforce, nonprofits’ AI adoption jumped from 12% to 55% in 2025 – a 43% increase in just one year. Organizations are using AI to enhance:
- Fundraising strategies
- Program design and delivery
- Volunteer coordination
- Impact reporting
- Marketing and communications
This growth reflects a sector that is increasingly embracing intelligent tools to amplify its reach and effectiveness.
Agents for Impact: Salesforce’s Commitment
To support this transformation, Salesforce launched the Agentforce Accelerator, a multi-million-dollar initiative that provides grants and donated technology to nonprofits. The goal is to help organizations build and deploy AI agents that drive measurable impact.
Humans for Impact, Agents for Scale
Agentforce is built on a powerful philosophy. AI should support and enhance human work, not replace it. These agents act as digital allies, handling repetitive tasks, surfacing insights, and enabling staff to focus on strategic and relationship-driven efforts.
Slack as the Agentic Operating System
Salesforce also showcased how Slack integrates with Agentforce to become the central hub for nonprofit collaboration. With Slackbots and Enterprise Search, teams can interact with AI agents using natural language, collaborate in real time, and access contextual data within their existing workflows.
Trust, Governance, and Data Integrity
Agentforce includes enterprise-grade governance features such as Agent Script, conditional logic, and context engineering. At its core is Data 360, a unified data layer that ensures privacy, compliance, and contextual intelligence. These tools help nonprofits maintain trust while scaling their operations with AI.
Claude, Gemini, and Copilot: AI Partnerships That Matter
Salesforce’s recent partnerships with Claude (Anthropic), Gemini (Google), and Copilot (Microsoft) are game changers for nonprofits. These integrations bring advanced, secure, and ethical AI capabilities directly into the Salesforce ecosystem, making intelligent automation more accessible and mission aligned.
- Claude offers trusted, privacy-conscious AI that’s ideal for nonprofits handling sensitive data. It can assist with donor communications, grant writing, and volunteer coordination within Salesforce’s secure environment.
- Gemini brings powerful multimodal reasoning and integrates seamlessly with Google Workspace and Slack. Nonprofits can automate complex workflows, generate insights from documents, and collaborate with AI agents in real time.
- Copilot from Microsoft enhances productivity by integrating directly into Salesforce and Microsoft 365. Nonprofits using Outlook, Teams, Word, or Excel can benefit from AI-generated meeting summaries, automated donor emails, and real-time CRM updates. This helps reduce administrative burden and improve collaboration across platforms.
Together, these partnerships represent a strategic shift toward scalable, secure, and ethical AI that nonprofits can trust. Whether managing sensitive data, coordinating volunteers, or crafting donor communications, these tools help organizations do more with fewer resources while maintaining compliance and mission alignment.
A Personal Perspective: A Foundation Finally in Place
Looking back over the past few years, it’s clear that Salesforce has been moving quickly, yet with intention, in its efforts to bring AI to market. Throughout this journey, the company has demonstrated a willingness to learn, adapt, and pivot.
The recent Agentforce 360 announcements at Dreamforce reflect a significant and promising shift. Combined with the strategic decision to reintegrate Nonprofit Cloud (Agentforce Nonprofit) into Salesforce’s core platform, these developments have laid a strong foundation for Agentforce. This move simplifies the overall architecture, aligns nonprofit solutions more closely with the broader Salesforce ecosystem, and creates the conditions for scalable, intelligent innovation.
It is a meaningful step forward, one that feels deliberate, well-considered, and built for the future.
Looking Ahead
Dreamforce 2025 made one thing clear. The future of nonprofit work is agentic. With the right tools, support, and mindset, organizations can unlock new levels of efficiency and impact. Salesforce’s Agentforce 360 offers a blueprint for this transformation, where technology amplifies humanity and mission-driven work thrives.
Looking for help with AI as an organization or just with Agentforce? Reach out to me, Ron Wille (ron.wille@rsmus.com) or visit rsmus.com to learn more.
Check out some of my other recent blog posts here:
- AI as a Teammate: Can Nonprofits finally be fully staffed?
- AI Is Here—What Nonprofits Can Learn from the Online Giving Era as AI Takes Hold
Ron Wille
Ron Wille, Jr. is a nonprofit technology strategist with over 20 years of experience helping associations, foundations, and social services organizations modernize operations. He specializes in CRM, fundraising, grants management, and marketing automation using platforms like Salesforce, Microsoft, HubSpot, and Marketing Cloud. Ron is passionate about guiding organizations through digital transformation and is now focused on helping them strategically align with AI to drive greater mission impact.
